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Life

IVF pioneer Jean Purdy made parenthood possible for millions. We must celebrate this unsung hero 

New film Joy takes steps towards recognising the scientist's crucial role in the reproduction revolution

In Joy, Bill Nighy plays Patrick Steptoe, Thomasin McKenzie is Jean Purdy and James Norton is Bob Edwards. Image: Netflix

I was born in Oldham General Hospital. That’s not big news, but few people know it was where the first IVF baby was born: Louise Joy Brown. Now that is big news. After I’d struggled to have a child and embarked on my own relentless, often hellish, IVF journey Oldham came back into my life. My husband Jack [Thorne, playwright and scriptwriter] asked if I’d get involved in piecing together the story of Joy, drawing on our experience where necessary. It was then I found out about the remarkable story of Jean Purdy.

Without IVF I wouldn’t be mum to my lovely eight-year-old son Elliott. He’s one of the 12 million IVF babies born since the miracle of Louise paved the way. But so few of us know the history of how our IVF babies got here; the years of painstaking commitment by physiologist Bob Edwards, obstetrician and gynaecologist Patrick Steptoe and the lesser-known embryologist Purdy. The world was against them and their ‘unethical’ ways, but these three mavericks persevered to change the face of reproduction.

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Their peers slammed them. The press vilified them. The church condemned them. When Edwards was awarded the Nobel Prize for Medicine in 2010 the Roman Catholic Church denounced the accolade. DNA pioneer James Watson saw their work as too big a risk, and one doctor at the time described the possibility of a new horrifying “thalidomide catastrophe”. Only their relentless drive and ingenuity saw them crack it.

Decades later, fertility looms large in the conversation in the States. As women’s bodies and choices are debated I’d like to pause and rewind back to the moment fertilisation outside the fallopian tube became a reality. And remember the extraordinary Purdy. The deeper I dug the more I realised it was yet another case of a woman being almost airbrushed out of history. Edwards and Steptoe wanted her recognised for her extraordinary contribution. In Edwards’ words: “There were three original pioneers in IVF and not just two.” But being intensely shy and private Purdy stayed in the background. She was happy caring for patients and their embryos while Edwards and Steptoe were the outward face of the project engaging in press and publicity.

Rachel Mason. Image: Craig Gibson

Of course men creating things and making history was de rigueur, but it was Purdy who not only spent hours supporting the brave women of the Ovum club, but was also the first person in the world to recognise and describe the formation of the human blastocyst. Louise Brown talks of her mum proudly describing Purdy as her first babysitter – keenly watching over the embryo growing through its different stages in the lab dish. Purdy developed systems and procedures that are now standard practice in IVF treatments.

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“It was no longer just Patrick and me. We had become a threesome… [she was] the patient, indomitable helper without whom none of our work would have been possible,” Edwards wrote in his 1989 autobiography. 

Jean died young at the age of 39 with no partner or children, making her invisibility cloak that much stronger. When it came to research for the film, finding anything about her was tough. She was such an introvert she instinctively shied away from publicity – she’d go and hide behind a magazine or anything rather than have her picture taken. 

We spoke to Grace MacDonald, mother of the first IVF boy Alastair, who through her time in Oldham became very close to Purdy (or Jeanie as she affectionately called her). She expressed how “doubly dedicated” Purdy was, looking after the embryos “like a mother hen”. I hope now she’s been given a voice alongside the plaques in Oldham that finally name her and recognise her for the crucial role she fulfilled. Edwards campaigned in 1980 for her name to be included, but his request was rejected until finally in March 2022 she was included, as was Sister Muriel Harris, another key female member of the team who was largely overlooked.

As I type away writing this in a coffee shop a group of four new mums sit bouncing their babies up and down comparing notes on their infants’ sleeping and feeding patterns. They’re all so tired I don’t think they know quite how loud they are but I’d take that sort of chat over the alternative any day.

And without Purdy, Edwards and Steptoe’s life-changing work, I wouldn’t have my baby-feeding log book to bore anyone with. And lastly I have to admit to being yet another woman who didn’t want to step forward and do any press around the film, so I can relate to Purdy’s reticence. But also as a woman, I knew that really I had to.

Joy is in select UK cinemas now and on Netflix from 22 November.

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